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Carl Byers

Carl Byers

Partner·F-Prime

Cambridge

Bio

Professional summary

Carl Byers is a Partner at F-Prime Capital, based in Cambridge. His official profile emphasizes his operating background in healthcare IT, especially as a founding team member and CFO at athenahealth from 1997 to 2010. At athenahealth, he led finance, legal, and corporate technology teams, helped build financial systems, raised multiple financing rounds, and led the company’s 2007 IPO. Earlier, he was a Senior Consultant at Booz Allen & Hamilton in financial services and health insurance. He teaches finance at Harvard’s Chan School of Public Health and has served on the Massachusetts Digital Health Council. He holds a BA from Wesleyan and a mid-career MPA from Harvard Kennedy School.

Investment focus

Stage, sector, and overall fit

Stage

Healthtech venture investments

Sector

Healthcare ITDigital healthHealthcare operationsHealthcare AI

Thesis

Healthcare ITDigital healthHealthcare services and technology-enabled care models

Notable companies

Selected portfolio companies the partner has backed

athenahealthCarrot FertilityCapital RxAmplifyMD

How to approach

Framing and angles for outreach

Pitch framing

Lead with a healthcare technology company that improves care delivery, workflow efficiency, payment integrity, or healthcare operations with a credible path to scale.

Personalization hooks

  1. 1Reference his athenahealth operator-to-investor background when discussing healthcare IT scale-up challenges.
  2. 2If relevant, connect to digital health infrastructure, AI-enabled healthcare workflows, or healthcare finance operations.

Recent signals

What the partner has said or done recently

  • Official profile lists recent featured impact content authored by him on digital health, AI agents in health, specialty care in the AI era, and Carrot Fertility.

Background

Career, education, and skills

Career history

  • F-Prime Capital PartnersPartner
  • athenahealth, Inc. (Nasdaq: ATHN)CFO (founding team)1997 - 2010
  • Booz, Allen & HamiltonSenior ConsultantPre-athenahealth
  • Harvard T.H. Chan School of Public HealthAdjunct Lecturer
  • Massachusetts Digital Health CouncilMember

Education

  • Wesleyan UniversityBA
  • Harvard Kennedy SchoolMid-Career MPA

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Chance Mathisen

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