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Colin Beirne

Colin Beirne

Partner·Two Sigma Ventures

Brooklyn, NY

Bio

Professional summary

Colin Beirne is a Partner at Two Sigma Ventures. The firm says he invests in companies building new products and solutions that use data and advanced computing, across sectors including fintech, enterprise and consumer AI, robotics and devices, real estate, and others. He joined Two Sigma in 2005 to help with business strategy and product expansion, began investing in private assets in 2007, and started building Two Sigma Ventures in 2011. Before Two Sigma, he worked in technology investment banking and corporate strategy. His current interests include data-driven healthcare, human-computer interfaces, and retail tech. He holds a dual BA in Economics and Law, Jurisprudence, and Social Thought from Amherst College and lives in Brooklyn.

Investment focus

Stage, sector, and overall fit

Stage

venture investing across data and advanced computing companies (official profile)

Sector

data sciencemachine learningadvanced computingfintechenterprise AIconsumer AIrobotics and devicesreal estatedata-driven healthcarehuman-computer interfacesretail tech

Thesis

data and advanced computingfintech, enterprise AI, consumer AI, robotics and devices, and real estatedata-driven healthcare, human-computer interfaces, and retail tech

Notable companies

Selected portfolio companies the partner has backed

Amper MusicAnsel HealthCoverWalletEnigmaKasistoPlacedPro.comWHOOPFormlogic

How to approach

Framing and angles for outreach

Pitch framing

Best fit for data-intensive startups where machine learning, advanced computing, or technical defensibility is central to the product and market wedge.

Personalization hooks

  1. 1Reference data and advanced computing as the core technical wedge.
  2. 2If relevant, connect to his stated interests in data-driven healthcare, human-computer interfaces, or retail tech.
  3. 3Brooklyn/New York operating context may be relevant for local founder outreach.

Background

Career, education, and skills

Career history

  • Deviation CapitalFounding Partner2025/2026 - Present
  • Two Sigma VenturesFounder & Partner2012 - 2025/2026

Education

  • Amherst CollegeB.A.

Skills

Data-driven investingEarly-stage ventureNYC tech ecosystemDeep techLife sciences

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