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Bio

Professional summary

Ed Mathers is a Partner on NEA’s healthcare team. NEA says he has been at the firm since 2008 and focuses on biotechnology and specialty pharmaceuticals investments. His official profile lists seed/early and growth as stages and includes healthcare as his sector. Before NEA, he served as EVP of Corporate Development and Venture at MedImmune, helped execute its sale to AstraZeneca, held licensing and acquisition roles at Inhale Therapeutic Systems, and spent 15 years at Glaxo Wellcome. He describes his healthcare interests as cutting-edge technologies across gene therapy, nonviral gene therapy, RNA editing, and immunology and inflammation.

Investment focus

Stage, sector, and overall fit

Stage

Seed/EarlyGrowth

Sector

HealthcareBiotechnologySpecialty pharmaceuticalsGene therapyRNA editingImmunology and inflammation

Thesis

Biotechnology and specialty pharmaceuticalsGene therapy, nonviral gene therapy, RNA editing, and immunology and inflammationHealthcare companies from seed/early through growth

Notable companies

Selected portfolio companies the partner has backed

AkouosAmplyx PharmaceuticalsCardurion PharmaceuticalsInversago PharmaLiquidiaMBX BiosciencesMirum PharmaceuticalsObsEvaRa PharmaceuticalsRhythm PharmaceuticalsSpliceBioSynlogic

How to approach

Framing and angles for outreach

Pitch framing

Pitch him with a rigorous biopharma company-building plan, strong scientific rationale, and a long-term development strategy for transformative healthcare technology.

Personalization hooks

  1. 1Reference his stated long-term, patient approach to company building.
  2. 2For gene therapy or RNA editing companies, connect directly to the areas he says excite him in healthcare.
  3. 3Mention his MedImmune corporate development background if the company has partnership, licensing, or M&A-relevant strategy.

Recent signals

What the partner has said or done recently

  • NEA’s current profile lists 2024 first investments in Brenig and Cardurion Pharmaceuticals and a 2025 first investment in Orbis Medicines.

  • NEA’s current profile lists MBX Biosciences as a 2020 first investment with current status IPO/Public on NASDAQ: MBX.

Background

Career, education, and skills

Career history

  • NEAPartner2008 - Present
  • MedImmuneEVP of Corporate Development and Venture
  • Inhale Therapeutic SystemsVP of Marketing and Corporate Licensing and Acquisitions
  • Glaxo WellcomeSales and marketing roles15 years

Skills

Healthcare investingBiotechnologySpecialty pharmaceuticalsCorporate developmentVenture investingLicensing and acquisitionsCompany buildingBiopharma commercialization

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