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Carlotta 'Lotti' Siniscalco
General Partner
Emergence Capital
Emergence general partner focused on fintech and B2B software investments.
Bio
Professional summary
Kevin Spain is a General Partner at Emergence Capital, where his official profile highlights investments including Doximity, Blend, and Augmedix. Emergence states that he remains on the board of Doximity and helped guide the company from its early days to the public markets. Before venture capital, Kevin co-founded and served as CEO of atMadison.com during the dot-com era. He also worked in Microsoft’s corporate development team and helped launch Electronic Arts’ original online gaming business. He is a Kauffman Fellow and holds an MBA from Wharton and an undergraduate degree from the University of Texas at Austin.
Investment focus
Stage, sector, and overall fit
Stage
Series Aearly growth
Sector
vertical SaaSindustry cloudhealthcare softwaresmall business software
Thesis
founder support through scalinggo-to-market and company-building strategyvertical and industry-specific software
Notable companies
Selected portfolio companies the partner has backed
DoximityBlendAugmedixPhysical IntelligenceLayer
How to approach
Framing and angles for outreach
Pitch framing
Lead with a disciplined company-building plan, especially if the company serves a specific industry or operational workflow. Kevin’s profile suggests he values founder empathy, steady support through difficult scaling moments, and businesses that can grow from startup to durable category leader.
Personalization hooks
- 1Reference Doximity as an example of scaling an industry-specific software company.
- 2If relevant, connect your pitch to his recent writing on autonomy in the built world or Physical Intelligence.
- 3Mention his founder experience at atMadison.com when discussing empathy for startup volatility.
- 4His official profile notes that he is a native Texan and enjoys barbecue and Southern food.
Recent signals
What the partner has said or done recently
Emergence lists his February 2026 writing on autonomy in the built world.
Emergence lists his November 2025 post on the firm’s investment in Physical Intelligence.
Emergence lists his July 2025 post on the firm’s investment in Layer.
Emergence lists his 2023 writing on GenAI solutions in healthcare.
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